A HILIC-Based UPLC/MS Method for the Separation of Lipid Classes from Plasma
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چکیده
IN T RO DU C T IO N Lipids play an important role in the energy storage, cellular signaling, and pathophysiology of diseases, such as cancer, neurodegenerative diseases, infections, diabetes, etc. Advances in LC/MS have allowed lipids to be studied with greater sensitivity and specificity. This alleviates the effects of co-eluting compounds and isobaric interference, and allows low abundance lipids to be more readily detected.
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تاریخ انتشار 2011